Assessment of Maternal Plasma Homocysteine levels among Sudanese Pregnant Ladies with Preeclampsia

Abstract

Objective: The aim of this study was to evaluate if there is association between preeclampsia and plasma homocysteine levels and moreover to investigate its association with the severity of the disease.

Material and method:   A case control study was performed on a total of 61 pregnant patients, classified to 31 preeclamptic ladies and 30 normotensive pregnant ladies. Homocysteine levels were assessed using A15 analyzer.

Results: Plasma homocysteine levels were significantly higher in preeclamptic ladies than normotensive pregnant ladies (13.25±4.35) μmol/L with significant difference (P.value: 0.000). Higher levels of plasma homocysteine with a mean (16.4585) μmol/L were associated to the severity preeclampsia with significant difference (P.value: 0.000).

Conclusion: Plasma homocysteine levels were significantly increased in preeclamptic ladies