Electrocardiographic Changes in Patients of Organophosphorus Compound Poisoning

Abstract

Background: The increase demand of crops has increased the use of chemicals in cultivation especially organophosphorus compounds. These chemicals have increased the incidence of poisoning among the persons who are handling these compounds. These incidences are usually accidental, suicidal or homicidal.

Objective of study: To study the ECG changes in Organophosphorus poisoning

Material &Method: It was a retrospective observational type of study. It was conducted in the department of casualty Liaquat university hospital Hyderabad. The study was conducted from September 2019 to December 2019. One hundred patients participated in this study. They were divided in two groups. In both control group and test group 50 patients were included

Result:  In the exposed group there were 14(28%) patients suffering from tachycardia, 7(14%) from bradycardia, 2(4%) from QT prolongation, 2(4%) from ST elevation, 2(4%) from extra systole, 2(4%) from T wave inversion, 4(4%) heart block, 3(6%) from MI, 14(28%) did not show any ECG changes. In the non-exposed group there were no ECG changes or cardiac effects were seen. The P value was 0.000.

Conclusion: It was concluded that Organophosphorus compounds increase the risk of myocardial damage which is reflected by ECG changes.