Antibacterial activity of new benzylbenzimidazole complexes against Gram-positive (+ve) and-negative (-ve) bacterial species isolated from surgical wounds of Iraqi patients
Pages : 1450-1452Download PDF
Antibiotics or antibacterial are a type of antimicrobial drug. Used to treat infections caused by germs (bacteria and certain parasites).They may either kill or inhibit the growth of those organism. Several types of antibiotics also possess antiprotozoal activity. In each year all over the world, millions of patients become infected with bacteria that are resistant to antibiotics and thousands of people die each year as a direct result of these infections. Prompting the researchers to find new antibiotics to confrontation like this challenge. So for the first time in this project we evaluate the effect of New complexes of VO+2, Co+2, Ni+2, Cu+2 and Ag+ with 1-benzylbenzimidazole (Bbz) were synthesized by reaction of the ligand with suitable metal sources against several selected human pathogenic bacterial species for both Gram-positive (+ve) and negative (-ve) bacteria isolated from surgical wounds. By using of disk diffusion technique our findings demonstrated that New complexes of VO+2, Co+2, Ni+2, Cu+2 and Ag+ with 1-benzylbenzimidazole (Bbz) showed inhibition for both Gram-positive (+ve) and negative (-ve) bacteria but varying effects of each compound.
Keywords: Benzylbenzimidazole, Antibacterial, Gram-positive and negative bacteria, Iraqi, patients