Article Published In Vol.2 (Nov-Dec-2014)

Design, Characterization and antimicrobial activity of Cu(II), Co(II) and Zn(II) complexes with Schiff base from 1,2-diphenylethane-1,2-dione and N-(1-Naphthyl) ethylenediamine

Author : Parveez Gull, Shaeel Ahmed AL-Thabaiti and Athar Adil Hashmi

Present work reviews the synthesis of Schiff base ligand derived from N-(1-Naphthyl) ethylenediamine with 1,2-diphenylethane-1,2-dione in the ratio of 1:2 and its metal complexes. The colored complexes prepared were of type [M2+L]X2, where M2+ = Cu, Co, Zn, L= Synthesised schiff base ligand and X= Cl. The chelation of the ligand to metal ions occurs through the four nitrogen atoms of the ligand. The structure of the obtained ligand and their respective metal complexes were elucidated by FTIR, elemental analysis, ultraviolet–visible spectra, conductometric measurements, magnetic susceptibility measurements and also 1HNMR spectral studies. The metal complex exhibits octahedral coordination geometrical arrangement. From spectral studies and molar conductance measurements, octahedral geometry was confirmed for Co(II) and square planar for Zn(II) complexes. Schiff base ligand and its metal complexes were screened against bacterial and fungal strains and their preliminary results showed that these complexes inhibited bacterial/fungal growth to a greater extent than the ligand.

Keywords: Schiff base, Ligand, metal complex, antimicrobial activity