Assessment of Coagulation Process in Diabetic Patients using Prothrombin Time and Activated Thromboplastin Time Tests
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Background: Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period.
Study design: This study was designed to determine effects of diabetes on coagulation process using prothrombin time test (PTT), and activated partial thromboblasin time test (APTT) and consent was taken from the health authority.
Materials and methods: Hundred blood samples were collected into EDTA blood containers 5 ml of venous blood were collected in plastic container containing 2.8 ml of aqueous tri-sodium citrate as anticoagulant. Blood was mixed and centrifuged at 4000 rpm for ten minutes, and platelet poor plasma was collected. PT and APTT were estimated using coagulometer.
Results: The results showed the mean of PT in diabetes was 12.609 in patients when was 13.905 in control, when the mean of APTT was32.745 in diabetic patients, when was 32.745 in control
Conclusion: From the present study it may concluded that diabetes mellitus had no effects on PT and APTT.
Keywords: Diabetes mellitus, prothrombin time, activated partial thromboblastin time.