Kinetic Study of the Micellar Catalysis and Effect upon Dephosphorylation of Diphosphate Ester by Peroxy AnionsDownload PDF
The Micellar catalysed reactions between hydroxide or hydroperoxide anions and diphosphate ester of 4-CDMPP has been examined in buffered medium (at pH 8 to 10) with borate ions. First order rate constant (Kψ) for the reaction of OH- with 4-CDMPP go through maxima with increasing the concentration of cetyltrimethyl ammonium-bromide (CTABr). Micelles of CTABr are very effective catalysts to the reactions of phosphate diester. Rate enhancement depends upon the hydrophobicity of the nucleophile for the reactions of phosphate diester. Rate constants measured with ions are approximately twice and thrice than that of OH- ions in presence of CTABr It has been known much early about the importance of organic phosphate esters as phospholipids, complex lipids (i.e. fatty acid esters containing phosphours, nitrogen bases or sugars) which have bee ascribed to spherical, helical and folded laminar type micelles.12 Many phospholipids exist in both and forms as well as different stereo chemical configurations which can be isolated in phospholipids13, diollipids14, sphingolipids15. An extensive amount of research carried out in recent years on chemical model system for specific enzymatic interactions16, similarities between nonionic micelles and globular proteins17 render micelles potentially useful as model for investigation of hydrophobic interaction. The micellar catalysis in all biochemical reactions may provide a basic model for interpretation for some aspects of metabolic process undergoing biochemical change in the body pass-through biogenesis of different types of natural surfactants. Since it is the easiest organism to handle in development of DNA to produce new organism in plants and flowers by fusing a particular gene to produce new DNA molecules. The most popular types of paste, cream, shampoo are currently employing sodiumlaurylsulphate as the detergent and sodiumstreate as the opacifying cream foaming agent and the thickening agents. Low molecular weight, cationic agents and detergent of the type have been used. Detergent to be use in tooth past must be specially purified and certified and inherently non-toxic. The cationic surface active agents for such diverse designificating purpose of designification in military and naval establishments, sterilization of instruments and skin surgery etc.
Keywords: Micelles, Miceller Catalyses, 4-CDMPP, CTABr, H2O2, Buffer Solution, Systeronics Spectrophotometer, IR-Spectra, NMR