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Article Published In Vol.5 (July-Aug-2017)

Synthesis and Determination of Antibacterial Activity of Jacaranone and Synthetic Analogs

Pages : 918-924

Author : María L. Arias, Rebeca Poveda and Jorge A. Cabezas

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Natural product jacaranone, 1, and five more analog derivatives were synthesized and its antibacterial activity against Gram-positive and Gram-negative microorganisms was tested. One of these derivatives, 5, was more active than the natural product, and exhibited a bactericidal effect against Gram-positive and Gram-negative bacteria.

Keywords: Jacaranone, jacaranone antimicrobial activity, jacaranone synthetic analogs

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