Role of Zinc and Copper in Infertility: An Update

Abstract

Extensive research has been conducted on the role of zinc and copper in the human health and diseases with more emphasis on reproductive health.  Deficiency of zinc in men results in reduced libido, low testosterone and sperm count and Cu/Zn ratio in body fluids plays a significant role in this aspect   Almost all endocrine glands plays a significant roles  in reproductive health with more emphasis on the role of LH, FSH, Prolactin, Testosterone, GH and erythrocyte enzymes of Cu/ Zn.  Both Cu/Zn deficiencies have been observed in a host of infectious diseases and these metals are low in diabetes mellitus.  This review article is the outcome of extensive literature search and compiling of key findings during the last 15 years.  The contents of this paper covers from a simple disease to the advanced cancer depicting the role  Zn/Cu in human health and diseases.  The content of this review article will serve as an eye opener to undertake more research in this   field.